You could try other visual differences, like make what you're interested in ball-and-stick, and everything else wireframe, like in this example:
.
.... Because, from: http://www.ysbl.york.ac.uk/~lohkamp/coot/doc/coot-python.html
procedure: hilight_binding_site (imol, centre_residue_spec,
hilight_colour, radius): hilight-colour is specified in degrees (round
the colour wheel - starting at yellow (e.g. 230 is purple))
It looks from this like you only get to choose Hue (color_map_rotation) and not Saturation or Lightness, even with the script interface.
However, text can be full RGB
3.28.3 (set-font-colour red green blue)
where:
red is an inexact number green is an inexact number blue is an inexact
number
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