star trek - Was the Borg destroyed at the end of Voyager?

We see the Borg Queen losing her limbs and her connection to the collective. However, we know that this doesn't amount to the destruction of the Borg. As pointed out in @jim's answer, the Queen is destroyed in First Contact (set in 2373) and then reappears in VOY ('Endgame' is set in 2378). Furthermore, the Borg obviously still exist in VOY after the Borg Queen has been killed in First Contact and is 're-incarnated' for want of a better word.

The only further reference we have to the Borg in canon is in Star Trek Countdown 3 where we learn the Narada was retrofitted with Borg technology. However, this doesn't tell us anything, other than that Borg technology still existed.

Memory Alpha tells us that the Queen's function is to order the Borg, so her removal would undoubtedly cause chaos for the Borg. However, the events of VOY following First Contact would indicate that she can be replaced.

The destruction of the Unicomplex we observe is likely because that is where the Borg Queen controls the Borg; without her, it is likely to crumble. We know that the Borg can repair their ships through thought, so the absence of the Queen resulting in the destruction of the Unicomplex is no surprise.

The agent that Admiral Janeway used to achieve all of this was a neurolytic pathogen, which, based on MA's description, likely only affected the Borg Queen and her control over the Borg.

So, based on this, my expectation would be that NO: the Borg were not destroyed at the end of Voyager, merely set back a fair way with their transwarp hub.