It is possible. According to this article, Alexander Sokurov's Faust (2011) was filmed entirely through a "color filter that lends it a faded tone, tending towards blues and greys and very, very stark whites." The film won the Golden Lion Award at the Venice Film Festival. The film may have been changed further through CGI, but this example answers the first part of your question.
http://zapadnik.wordpress.com/2012/02/11/alexander-sokurovs-faust/
I have seen some references to the move Safe House being shot with colored filters, but I have not been able to confirm with an authoritative source.
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